human FHIT Adenovirus

Name
Ad-h-FHIT

Cat No
ADV-209008

Availability
4-5 weeks

This is an Adenovirus expressing Human FHIT.

ADV-209008

Ad-h-FHIT

Ready-to-use Adenovirus expressing Human FHIT (fragile histidine triad). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

AP3Aase; FRA3B

Description (Vector)

This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.

Gene ID

2272

Gene Name (Vector)

fragile histidine triad

Gene Symbol

FHIT

HGNC ID

HGNC:3701

ORF Size (aa)

444

RefSeq ID

NM_002012

RefSeq Synonyms

NM_002012, NM_001320901, NM_001320900, NM_001320899, NM_001166243, BC032336,

Species

human

UniGene ID

Hs.715597

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.