human F5 Adenovirus

Name
Ad-h-F5

Cat No
ADV-208232

Availability
4-5 weeks

This is an Adenovirus expressing Human CCDC8.

ADV-208232

Ad-h-F5

Ready-to-use Adenovirus expressing Human F5 (coagulation factor V). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

FVL; PCCF; RPRGL1; THPH2

Description (Vector)

F5 encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance.

Gene ID

2153

Gene Name (Vector)

coagulation factor V

Gene Symbol

HGNC ID

HGNC:3542

ORF Size (aa)

6675

ORF Size (bp)

6675 bp

RefSeq ID

NM_000130

RefSeq Synonyms

NM_000130, BC113357, BC111929, BC111588, BC111461,

Species

human

UniGene ID

Hs.30054

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.