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human EFTUD1 Adenovirus

Name 
Ad-h-EFTUD1
Cat No 
ADV-207653
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human EFTUD1.

ADV-207653
Ad-h-EFTUD1

Ready-to-use Adenovirus expressing Human EFL1 (elongation factor like GTPase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
EFL1; EFTUD1; elongation factor Tu GTP binding domain containing 1; elongation factor Tu GTP-binding domain-containing protein 1; elongation factor-like 1; elongation factor-like GTPase 1; FAM42A; HsT19294; RIA1; ribosome assembly 1 homolog; SDS2
Description (eCommerce)
EFTUD1 is involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q7Z2Z2].
Gene ID
79631
Gene Name (eCommerce)
elongation factor like GTPase 1
Gene Name (Vector)
elongation factor like GTPase 1
Gene Symbol
EFL1
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3360
ORF Size (bp)
3360 bp
Protein Name (eCommerce)
Elongation factor-like GTPase 1
RefSeq ID
NM_024580
RefSeq Synonyms
NM_024580, NM_001322845, NM_001322844, NM_001040610, BC156743, BC152910,
Research Areas
Cell Biology,Translational Control
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
EFTUD1 is involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q7Z2Z2].
UniGene ID
Hs.459114
UniProt ID (eCommerce)
Q7Z2Z2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.