human EFNB3 Adenovirus
This is an Adenovirus expressing Human EFNB3.
ADV-207647
Ad-h-EFNB3
Ready-to-use Adenovirus expressing Human EFNB3 (ephrin B3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EFL6; EPLG8; LERK8
Description (Vector)
EFNB3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. Moreover, since levels of EFNB3 expression were particularly high in several forebrain subregions compared to other brain subregions, it may play a pivotal role in forebrain function. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH Receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
Gene ID
1949
Gene Name (Vector)
ephrin B3
Gene Symbol
EFNB3
HGNC ID
HGNC:3228
ORF Size (aa)
1023
ORF Size (bp)
1023 bp
RefSeq ID
NM_001406
RefSeq Synonyms
NM_001406, BC042944,
Species
human
UniGene ID
Hs.26988
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.