human E2F6 Adenovirus
This is an Adenovirus expressing Human E2F6.
ADV-207498
Ad-h-E2F6
Ready-to-use Adenovirus expressing Human E2F6 (E2F transcription factor 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
E2F-6
Description (Vector)
E2F6 encodes a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins. They are also a target of the transforming proteins of small DNA tumor viruses. Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max. Multiple transcript variants have been reported for this gene, but it has not been clearly demonstrated that they encode valid isoforms.
Gene ID
1876
Gene Name (Vector)
E2F transcription factor 6
Gene Symbol
E2F6
HGNC ID
HGNC:3120
ORF Size (aa)
846
ORF Size (bp)
846 bp
RefSeq ID
NM_198256
RefSeq Synonyms
NM_212540, NM_198256, NM_001278278, NM_001278277, NM_001278276, NM_001278275, BC107740, BC008348,
Species
human
UniGene ID
Hs.603093
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.