human DUSP5 Adenovirus
This is an Adenovirus expressing Human DUSP5.
ADV-207436
Ad-h-DUSP5
Ready-to-use Adenovirus expressing Human DUSP5 (dual specificity phosphatase 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DUSP; HVH3
Description (Vector)
DUSP5 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.
Gene ID
1847
Gene Name (Vector)
dual specificity phosphatase 5
Gene Symbol
DUSP5
HGNC ID
HGNC:3071
ORF Size (aa)
1155
ORF Size (bp)
1155 bp
RefSeq ID
NM_004419
RefSeq Synonyms
NM_004419, BC062545,
Species
human
UniGene ID
Hs.2128
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.