human DUOX1 Adenovirus
This is an Adenovirus expressing Human DUOX1.
ADV-207394
Ad-h-DUOX1
Ready-to-use Adenovirus expressing Human DUOX1 (dual oxidase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
LNOX1; NOXEF1; THOX1
Description (Vector)
DUOX1 is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
Gene ID
53905
Gene Name (Vector)
dual oxidase 1
Gene Symbol
DUOX1
HGNC ID
HGNC:3062
ORF Size (aa)
4656
ORF Size (bp)
4656 bp
RefSeq ID
NM_017434
RefSeq Synonyms
NM_175940, NM_017434, BC114938, BC114628,
Species
human
UniGene ID
Hs.272813
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.