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human DSG2 Adenovirus

Name 
Ad-h-DSG2
Cat No 
ADV-207351
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human DSG2.

ADV-207351
Ad-h-DSG2

Ready-to-use Adenovirus expressing Human DSG2 (desmoglein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
cadherin family member 5; CDHF5; desmoglein-2; HDGC
Description (eCommerce)
Desmoglein-2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells [taken from NCBI Entrez Gene (Gene ID: 1829)].
Description (Vector)
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.
Gene ID
1829
Gene Name (eCommerce)
desmoglein 2
Gene Name (Vector)
desmoglein 2
Gene Symbol
DSG2
HGNC ID
HGNC:3049
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3357
ORF Size (bp)
3357 bp
Protein Name (eCommerce)
Desmoglein-2
RefSeq ID
NM_001943
RefSeq Synonyms
NM_001943, BC099657, BC099656, BC099655,
Research Areas
Apoptosis,Cardiology,Cardiomyopathy,Cardiovascular,EGFR Signaling,Signal Transduction
Research Areas (Faceted)
cardiovascular,cell_biology,signal_transduction
Species
human
Target Sentence
Desmoglein-2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells [taken from NCBI Entrez Gene (Gene ID: 1829)].
UniGene ID
Hs.412597
UniProt ID (eCommerce)
Q14126

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.