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human DISC1 Adenovirus

Name 
Ad-h-DISC1
Cat No 
ADV-207013
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human DISC1.

ADV-207013
Ad-h-DISC1

Ready-to-use Adenovirus expressing Human DISC1 (disrupted in schizophrenia 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C1orf136; SCZD9
Description (Vector)
DISC1 encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. DISC1 is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID
27185
Gene Name (Vector)
disrupted in schizophrenia 1
Gene Symbol
DISC1
HGNC ID
HGNC:2888
ORF Size (aa)
2499
ORF Size (bp)
2499 bp
RefSeq ID
NM_018662
RefSeq Synonyms
NM_018662, NM_001164556, NM_001164555, NM_001164554, NM_001164553, NM_001164552, NM_001164551, NM_001164550, NM_001164549, NM_001164548, NM_001164547, NM_001164546, NM_001164545, NM_001164544, NM_001164542, NM_001164541, NM_001164540, NM_001164539, NM_001164538, NM_001164537, NM_001012959, NM_001012958, NM_001012957, BC151225,
Species
human
UniGene ID
Hs.13318

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.