human DGUOK Adenovirus
This is an Adenovirus expressing Human DGUOK.
ADV-206929
Ad-h-DGUOK
Ready-to-use Adenovirus expressing Human DGUOK (deoxyguanosine kinase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
dGK; MTDPS3; NCPH; PEOB4
Description (Vector)
In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.
Gene ID
1716
Gene Name (Vector)
deoxyguanosine kinase
Gene Symbol
DGUOK
HGNC ID
HGNC:2858
ORF Size (aa)
834
ORF Size (bp)
834 bp
RefSeq ID
NM_080916
RefSeq Synonyms
NM_080918, NM_080916, NM_001318863, NM_001318862, NM_001318861, NM_001318860, NM_001318859, BC015757, BC001121,
Species
human
UniGene ID
Hs.469022
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.