human DEFA1 Adenovirus
This is an Adenovirus expressing Human DEFA1.
ADV-206790
Ad-h-DEFA1
Ready-to-use Adenovirus expressing Human DEFA1 (defensin alpha 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DEF1; DEFA2; HNP-1; HP-1; HP1; MRS
Description (Vector)
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.
Gene ID
1667
Gene Name (Vector)
defensin alpha 1
Gene Symbol
DEFA1
HGNC ID
HGNC:2761
ORF Size (aa)
285
RefSeq ID
NM_004084
RefSeq Synonyms
NM_004084, BC112188, BC093791, BC069423,
Species
human
UniGene ID
Hs.380781
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.