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human DDX41 Adenovirus

Name 
Ad-h-DDX41
Cat No 
ADV-206760
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human DDX41.

ADV-206760
Ad-h-DDX41

Ready-to-use Adenovirus expressing Human DDX41 (DEAD-box helicase 41). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ABS; DEAD (Asp-Glu-Ala-Asp) box polypeptide 41; DEAD box protein 41; DEAD box protein abstrakt homolog; DEAD-box protein abstrakt; MPLPF; probable ATP-dependent RNA helicase DDX41; putative RNA helicase
Description (eCommerce)
DDX41 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. The function of DDX41 has not been determined.
Description (Vector)
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Based on studies in Drosophila, the abstrakt gene is widely required during post-transcriptional gene expression.
Gene ID
51428
Gene Name (eCommerce)
DEAD-box helicase 41
Gene Name (Vector)
DEAD-box helicase 41
Gene Symbol
DDX41
HGNC ID
HGNC:18674
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1869
ORF Size (bp)
1869 bp
Protein Name (eCommerce)
Probable ATP-dependent RNA helicase DDX41
RefSeq ID
NM_016222
RefSeq Synonyms
NM_016222, NM_001321830, NM_001321732, BC015476,
Research Areas
Apoptosis,Gene Expression,Helicase Activity,Host-Virus Interactions,IFN Signaling,Immunology,Innate Immunity,mRNA Processing,mRNA Splicing,Response to Virus,RNA Binding,RNA Processing,Signal Transduction,Spliceosome,Zinc-finger
Research Areas (Faceted)
signal_transduction,cell_biology,genetics,transcription_translation,cell_biology,infectious_disease,immunology,signal_transduction,genetics,transcription_translation,infectious_disease,cell_biology
Species
human
Target Sentence
DDX41 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. The function of DDX41 has not been determined.
UniGene ID
Hs.484288
UniProt ID (eCommerce)
Q9UJV9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.