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human DDX19B Adenovirus

Name 
Ad-h-DDX19B
Cat No 
ADV-206736
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human DDX19B.

ADV-206736
Ad-h-DDX19B

Ready-to-use Adenovirus expressing Human DDX19B (DEAD-box helicase 19B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ATP-dependent RNA helicase DDX19; ATP-dependent RNA helicase DDX19B; DBP5; DDX19; DEAD (Asp-Glu-Ala-As) box polypeptide 19B; DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B; DEAD box protein 19B; DEAD box RNA helicase DEAD5; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (Dbp5, yeast, homolog); DEAD-box protein 5; DEAD-box RNA helicase DEAD5; RNAh; yeast Dbp5 homolog
Description (eCommerce)
DDX19 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX19 may be involved in mRNA transport.
Description (Vector)
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
11269
Gene Name (eCommerce)
DEAD-box helicase 19B
Gene Name (Vector)
DEAD-box helicase 19B
Gene Symbol
DDX19B
HGNC ID
HGNC:2742
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1113
ORF Size (bp)
1113 bp
Protein Name (eCommerce)
ATP-dependent RNA helicase DDX19B
RefSeq ID
NM_007242
RefSeq Synonyms
NM_007242, NM_001257175, NM_001257174, NM_001257173, NM_001257172, NM_001014451, NM_001014449, BC010008, BC003626,
Research Areas
Helicase Activity,mRNA transport,Nuclear Import/Export,RNA Binding,RNA Processing,RNA Transport,Transport
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
DDX19 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX19 may be involved in mRNA transport.
UniGene ID
Hs.221761
UniProt ID (eCommerce)
Q9UMR2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.