human DDR2 Adenovirus
This is an Adenovirus expressing Human DDR2.
ADV-206718
Ad-h-DDR2
Ready-to-use Adenovirus expressing Human DDR2 (discoidin domain receptor tyrosine kinase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MIG20a; NTRKR3; TKT; TYRO10
Description (Vector)
Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.
Gene ID
4921
Gene Name (Vector)
discoidin domain receptor tyrosine kinase 2
Gene Symbol
DDR2
HGNC ID
HGNC:2731
ORF Size (aa)
2568
ORF Size (bp)
2568 bp
RefSeq ID
NM_006182
RefSeq Synonyms
NM_006182, NM_001014796, BC052998,
Species
human
UniGene ID
Hs.593833
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.