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human CYP3A5 Adenovirus

Name 
Ad-h-CYP3A5
Cat No 
ADV-206506
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human CYP3A5.

ADV-206506
Ad-h-CYP3A5

Ready-to-use Adenovirus expressing Human CYP3A5 (cytochrome P450 family 3 subfamily A member 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CP35; CYPIIIA5; P450PCN3; PCN3
Description (Vector)
This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene, CYP3A5P1, which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. Multiple alternatively spliced transcript variants have been identified for this gene.
Gene ID
1577
Gene Name (Vector)
cytochrome P450 family 3 subfamily A member 5
Gene Symbol
CYP3A5
HGNC ID
HGNC:2638
ORF Size (aa)
1509
ORF Size (bp)
1509 bp
RefSeq ID
NM_000777
RefSeq Synonyms
NM_001291830, NM_001291829, NM_001190484, NM_000777, BC033862,
Species
human
UniGene ID
Hs.695915

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.