human CYP1A1 Adenovirus
This is an Adenovirus expressing Human CYP1A1.
ADV-206450
Ad-h-CYP1A1
Ready-to-use Adenovirus expressing Human CYP1A1 (cytochrome P450 family 1 subfamily A member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX
Description (Vector)
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.
Gene ID
1543
Gene Name (Vector)
cytochrome P450 family 1 subfamily A member 1
Gene Symbol
CYP1A1
HGNC ID
HGNC:2595
ORF Size (aa)
1539
ORF Size (bp)
1539 bp
RefSeq ID
NM_000499
RefSeq Synonyms
NM_001319217, NM_001319216, NM_000499, BC023019,
Species
human
UniGene ID
Hs.72912
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.