human CRTC3 Adenovirus

Name 
Ad-h-CRTC3
Cat No 
ADV-206040
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human BPIFB4.

ADV-206040
Ad-h-CRTC3

Ready-to-use Adenovirus expressing Human CRTC3 (CREB regulated transcription coactivator 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CREB-regulated transcription coactivator 3; TORC3; TORC-3; Transducer of CREB protein 3; transducer of regulated cAMP response element-binding protein (CREB) 3; Transducer of regulated cAMP response element-binding protein 3; transducer of regulated CREB protein 3
Description (eCommerce)
TORC3 (transducer of regulated cAMP response element-binding protein 3) is a transcriptional coactivator for CREB1 which activates transcription through cAMP response element (CRE) sites. TORC3 acts as a coactivator in the SIK/TORC signaling pathway. TORC3 has also been shown to be a coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
Description (Vector)
CRTC3 is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Gene ID
64784
Gene Name (eCommerce)
CREB regulated transcription coactivator 3
Gene Name (Vector)
CREB regulated transcription coactivator 3
Gene Symbol
CRTC3
HGNC ID
HGNC:26148
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
963
ORF Size (bp)
963 bp
Protein Name (eCommerce)
CREB-regulated transcription coactivator 3
RefSeq ID
NM_022769
RefSeq Synonyms
NM_022769, NM_001042574, BC074731,
Research Areas
Host-Virus Interactions,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,infectious_disease,transcription_translation
Species
human
Target Sentence
TORC3 (transducer of regulated cAMP response element-binding protein 3) is a transcriptional coactivator for CREB1 which activates transcription through cAMP response element (CRE) sites. TORC3 acts as a coactivator in the SIK/TORC signaling pathway. TORC3 has also been shown to be a coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
UniGene ID
Hs.567572
UniProt ID (eCommerce)
Q6UUV7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.