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human COQ6 Adenovirus

Name 
Ad-h-COQ6
Cat No 
ADV-205789
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human COQ6.

ADV-205789
Ad-h-COQ6

Ready-to-use Adenovirus expressing Human COQ6 (coenzyme Q6, monooxygenase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CGI-10; CGI10; COQ10D6
Description (Vector)
COQ6 belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene ID
51004
Gene Name (Vector)
coenzyme Q6, monooxygenase
Gene Symbol
COQ6
HGNC ID
HGNC:20233
ORF Size (aa)
1407
ORF Size (bp)
1407 bp
RefSeq ID
NM_182476
RefSeq Synonyms
NM_182480, NM_182476, BC014483, BC014181,
Species
human
UniGene ID
Hs.632335

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.