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human COBL Adenovirus

Name 
Ad-h-COBL
Cat No 
ADV-205659
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human COBL.

ADV-205659
Ad-h-COBL

Ready-to-use Adenovirus expressing Human COBL (cordon-bleu WH2 repeat protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
protein cordon-bleu
Description (eCommerce)
COBL contains WH2 domains (WASP, Wiskott-Aldrich syndrome protein, homology domain-2) that interact with actin. COBL is required for growth and assembly of brush border microvilli that play a role in maintaining intestinal homeostasis. A similar protein in mouse functions in midbrain neural tube closure [taken from NCBI Entrez Gene (Gene ID: 23242)].
Gene ID
23242
Gene Name (eCommerce)
cordon-bleu WH2 repeat protein
Gene Name (Vector)
cordon-bleu WH2 repeat protein
Gene Symbol
COBL
HGNC ID
HGNC:22199
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3816
ORF Size (bp)
3816 bp
Protein Name (eCommerce)
Protein cordon-bleu
RefSeq ID
NM_015198
RefSeq Synonyms
NM_015198, NM_001346444, NM_001346443, NM_001346442, NM_001346441, NM_001287438, NM_001287436, BC150263, BC144099, BC136441,
Research Areas
Cytoskeleton,Neurobiology,Neurodevelopment
Research Areas (Faceted)
cell_biology,neurobiology,developmental_biology
Species
human
Target Sentence
COBL contains WH2 domains (WASP, Wiskott-Aldrich syndrome protein, homology domain-2) that interact with actin. COBL is required for growth and assembly of brush border microvilli that play a role in maintaining intestinal homeostasis. A similar protein in mouse functions in midbrain neural tube closure [taken from NCBI Entrez Gene (Gene ID: 23242)].
UniGene ID
Hs.99141
UniProt ID (eCommerce)
O75128

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.