human CLOCK Adenovirus
This is an Adenovirus expressing Human CLOCK.
ADV-205493
Ad-h-CLOCK
Ready-to-use Adenovirus expressing Human CLOCK (clock circadian regulator). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
bHLHe8; circadian locomoter output cycles kaput protein; circadian locomoter output cycles protein kaput; class E basic helix-loop-helix protein 8; clock homolog; hCLOCK; KAT13D
Description (eCommerce)
CLOCK (circadian locomotor output cycles protein kaput) belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1 [taken from NCBI Entrez Gene (GeneID: 9575)].
Description (Vector)
CLOCK product regulates circadian rhythm and metabolism. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and a DNA binding histone acetyltransferase. Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome. Alternative splicing results in multiple transcript variants.
Gene ID
9575
Gene Name (eCommerce)
clock circadian regulator
Gene Name (Vector)
clock circadian regulator
Gene Symbol
CLOCK
HGNC ID
HGNC:2082
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2541
ORF Size (bp)
2541 bp
Protein Name (eCommerce)
Circadian locomoter output cycles protein kaput
RefSeq ID
NM_004898
RefSeq Synonyms
NM_004898, NM_001267843, BC126159, BC126157, BC041878,
Research Areas
Acyltransferase,DNA Damage/Repair,Host-Virus Interactions,Immunology,Metabolism/Metabolic Process,Neurobiology,RNA Binding,Signal Transduction,Transcription Factor/Regulator
Research Areas (Faceted)
signal_transduction,cell_biology,genetics,transcription_translation,infectious_disease,immunology,metabolism,neurobiology,genetics,transcription_translation
Species
human
Target Sentence
CLOCK (circadian locomotor output cycles protein kaput) belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1 [taken from NCBI Entrez Gene (GeneID: 9575)].
UniGene ID
Hs.436975
UniProt ID (eCommerce)
O15516
Recently Viewed Products
AAV-m-NSMCE2-shRNA
Cat No: shAAV-266116
AAV-h-MCEE-shRNA
Cat No: shAAV-215163
Ad-h-CLTC
Cat No: ADV-205527
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.