human CISH Adenovirus
This is an Adenovirus expressing Human CISH.
ADV-205295
Ad-h-CISH
Ready-to-use Adenovirus expressing Human CISH (cytokine inducible SH2 containing protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BACTS2; CIS; CIS-1; G18; SOCS
Description (Vector)
CISH contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
1154
Gene Name (Vector)
cytokine inducible SH2 containing protein
Gene Symbol
CISH
HGNC ID
HGNC:1984
ORF Size (aa)
777
ORF Size (bp)
777 bp
RefSeq ID
NM_013324
RefSeq Synonyms
NM_145071, NM_013324, BC064354, BC031590,
Species
human
UniGene ID
Hs.655334
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.