Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

CCT4

Gene Name

chaperonin containing TCP1 subunit 4

Gene ID

10575

Gene Synonyms

CCT-DELTA; Cctd; SRB

ORF Size

1620 bp

RefSeq#

BC106934

Gene Description

The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 (PubMed 9819444)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.421509

HGNC ID

HGNC:1617