human CCL2 Adenovirus

Name
Ad-h-CCL2

Cat No
ADV-204430

Availability
4-5 weeks

This is an Adenovirus expressing Human CCL2.

ADV-204430

Ad-h-CCL2

Ready-to-use Adenovirus expressing Human CCL2 (C-C motif chemokine ligand 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF

Description (Vector)

CCL2 is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.

Gene ID

6347

Gene Name (Vector)

C-C motif chemokine ligand 2

Gene Symbol

CCL2

HGNC ID

HGNC:10618

ORF Size (aa)

300

RefSeq ID

NM_002982

RefSeq Synonyms

NM_002982, BC009716,

Species

human

UniGene ID

Hs.303649

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.