human BRIP1 Adenovirus

Name 
Ad-h-BRIP1
Cat No 
ADV-202271
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human AQP12A.

ADV-202271
Ad-h-BRIP1

Ready-to-use Adenovirus expressing Human BRIP1 (BRCA1 interacting protein C-terminal helicase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ATP-dependent RNA helicase BRIP1; BACH1; BRCA1/BRCA2-associated helicase 1; BRCA1-associated C-terminal helicase 1; BRCA1-binding helicase-like protein BACH1; BRCA1-interacting protein 1; BRCA1-interacting protein C-terminal helicase 1; FANCJ; Fanconi anemia group J protein; OF; Protein FACJ
Description (eCommerce)
BRCA1-interacting protein 1 (BRIP1) is a RecQ DNA helicase that associates with BRCA1 and functions in double-strand break repair and the maintenance of chromosomal stability. BRIP1 has been found to be deficient in Fanconi anemia (FA), a chromosomal instability syndrome associated with a strong predisposition to cancer.
Description (Vector)
BRIP1 is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). This gene may be a target of germline cancer-inducing mutations.
Gene ID
83990
Gene Name (eCommerce)
BRCA1 interacting protein C-terminal helicase 1
Gene Name (Vector)
BRCA1 interacting protein C-terminal helicase 1
Gene Symbol
BRIP1
HGNC ID
HGNC:20473
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3750
ORF Size (bp)
3750 bp
Protein Name (eCommerce)
Fanconi anemia group J protein
RefSeq ID
NM_032043
RefSeq Synonyms
NM_032043, BC101474, BC101472,
Research Areas
DNA Damage/Repair,Fanconi anemia,Helicase Activity,Transcription Factor/Regulator
Research Areas (Faceted)
genetics,transcription_translation,cell_biology
Species
human
Target Sentence
BRCA1-interacting protein 1 (BRIP1) is a RecQ DNA helicase that associates with BRCA1 and functions in double-strand break repair and the maintenance of chromosomal stability. BRIP1 has been found to be deficient in Fanconi anemia (FA), a chromosomal instability syndrome associated with a strong predisposition to cancer.
UniGene ID
Hs.532799
UniProt ID (eCommerce)
Q9BX63

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.