human BMI1 Adenovirus

Name 
Ad-h-BMI1
Cat No 
ADV-202181
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human APOBEC3F.

ADV-202181
Ad-h-BMI1

Ready-to-use Adenovirus expressing Human BMI1 (BMI1 proto-oncogene, polycomb ring finger). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
B lymphoma Mo-MLV insertion region 1 homolog; BMI1 polycomb ring finger oncogene; BMI1 polycomb ring finger proto-oncogene; FLVI2/BMI1; flvi-2/bmi-1; murine leukemia viral (bmi-1) oncogene homolog; PCGF4; polycomb complex protein BMI-1; polycomb group protein Bmi1; polycomb group RING finger protein 4; ring finger protein 51; RNF51
Description (eCommerce)
BMI1 (B lymphoma Mo-MLV insertion region 1 homolog) is a core component of the polycomb group (PcG) multiprotein PRC1 complex which plays an important role in transcriptional repression of gene expression during development. BMI1 association with RING protein 1B is important to the E3 ligase activity of RING1B in the PRC1 complex. BMI1 is an oncogene whose overexpression is associated with many types of human tumors and is a stem-cell marker and regulator of stem cell self-renewal.
Gene ID
648
Gene Name (eCommerce)
BMI1 proto-oncogene, polycomb ring finger
Gene Name (Vector)
BMI1 proto-oncogene, polycomb ring finger
Gene Symbol
BMI1
HGNC ID
HGNC:1066
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
981
ORF Size (bp)
981 bp
Protein Name (eCommerce)
Polycomb complex protein BMI-1
RefSeq ID
NM_005180
RefSeq Synonyms
NM_005180, BC011652,
Research Areas
Apoptosis,Autophagy,Brain Development,Cancer,Complexome,Gene Expression,Histone Modification,Immunology,MicroRNAs in Cancer,Neurobiology,Neurodevelopment,Polycomb Proteins,Transcription Factor/Regulator,Transcriptional Misregulation in Cancer,Tumor Suppressors/Oncoproteins,Zinc-finger
Research Areas (Faceted)
cancer,cell_biology,developmental_biology,genetics,immunology,neurobiology,transcription_translation
Species
human
Target Sentence
BMI1 (B lymphoma Mo-MLV insertion region 1 homolog) is a core component of the polycomb group (PcG) multiprotein PRC1 complex which plays an important role in transcriptional repression of gene expression during development. BMI1 association with RING protein 1B is important to the E3 ligase activity of RING1B in the PRC1 complex. BMI1 is an oncogene whose overexpression is associated with many types of human tumors and is a stem-cell marker and regulator of stem cell self-renewal.
UniGene ID
Hs.380403
UniProt ID (eCommerce)
P35226

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.