human BACE2 Adenovirus
Category: Adenovirus > Over-Expression
Cat. No: ADV-201931
Availability:
3-5 weeks
Name:
Ad-h-BACE2
This is an Adenovirus expressing Human BACE2.
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Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- CMV
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- BACE2
- Gene Name
- beta-site APP-cleaving enzyme 2
- Gene ID
- 25825
- Gene Synonyms
- AEPLC; ALP56; ASP1; ASP21; BAE2; CDA13; CEAP1; DRAP
- ORF Size
- 1557 bp
- RefSeq#
- BC014453
- Gene Description
- Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene.
- UniGene ID
- Hs.529408
- HGNC ID
- HGNC:934
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-CMV-Luc | 1000 |
Ad-GFP | 1060 |
Ad-CMV-b-Gal | 1080 |
Ad-Null | 1240 |
Ad-CMV-Null | 1300 |
Ad-RFP | 1660 |
Ad-CFP | 1766 |
Ad-mCherry | 1767 |
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