human ASAH2 Adenovirus

Name 
Ad-h-ASAH2
Cat No 
ADV-201507
Availability
4-5 weeks

This is an Adenovirus expressing Human ALS2CL.

ADV-201507
Ad-h-ASAH2

Ready-to-use Adenovirus expressing Human ASAH2 (N-acylsphingosine amidohydrolase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BCDase; HNAC1; LCDase; N-CDase; NCDase
Description (Vector)
Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 (PubMed 11328816)).(supplied by OMIM, Mar 2008)
Gene ID
56624
Gene Name (Vector)
N-acylsphingosine amidohydrolase 2
Gene Symbol
ASAH2
HGNC ID
HGNC:18860
ORF Size (aa)
2181
ORF Size (bp)
2181 bp
RefSeq ID
NM_019893
RefSeq Synonyms
NM_019893, NM_001143974, BC107105,
Species
human
UniGene ID
Hs.512645

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.