human ARRB2 Adenovirus

Name 
Ad-h-ARRB2
Cat No 
ADV-201476
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human ARRB2.

ADV-201476
Ad-h-ARRB2

Ready-to-use Adenovirus expressing Human ARRB2 (arrestin beta 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ARB2; ARR2; arrestin 3; Arrestin beta-2; BARR2; beta-arrestin-2; non-visual arrestin-3
Description (eCommerce)
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Beta-arrestin 2, like beta-arrestin 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for beta-arrestin 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. [taken from NCBI Entrez Gene (Gene ID: 409)].
Gene ID
409
Gene Name (eCommerce)
arrestin beta 2
Gene Name (Vector)
arrestin beta 2
Gene Symbol
ARRB2
HGNC ID
HGNC:712
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1230
ORF Size (bp)
1230 bp
Protein Name (eCommerce)
Beta-arrestin-2
RefSeq ID
NM_004313
RefSeq Synonyms
NM_199004, NM_004313, NM_001330064, NM_001257331, NM_001257330, NM_001257329, NM_001257328, BC067368, BC007427,
Research Areas
Cancer,Cardiology,Cardiovascular,Hedgehog Signaling,Immunology,Interleukin Signaling,MAPK Signaling,Neurobiology,NF-kB Signaling,Notch Signaling,Signal Transduction,TGF-beta Signaling,Toll-like Receptor Signaling,Ubiquitination,Wnt Signaling
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,developmental_biology,immunology,neurobiology,signal_transduction
Species
human
Target Sentence
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Beta-arrestin 2, like beta-arrestin 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for beta-arrestin 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. [taken from NCBI Entrez Gene (Gene ID: 409)].
UniGene ID
Hs.435811
UniProt ID (eCommerce)
P32121

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.