human APRT Adenovirus

Name 
Ad-h-APRT
Cat No 
ADV-201225
Availability
4-5 weeks

This is an Adenovirus expressing Human AK4.

ADV-201225
Ad-h-APRT

Ready-to-use Adenovirus expressing Human APRT (adenine phosphoribosyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AMP; APRTD
Description (Vector)
Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
353
Gene Name (Vector)
adenine phosphoribosyltransferase
Gene Symbol
APRT
HGNC ID
HGNC:626
ORF Size (aa)
543
ORF Size (bp)
543 bp
RefSeq ID
NM_000485
RefSeq Synonyms
NM_001030018, NM_000485, BC107151, BC106894,
Species
human
UniGene ID
Hs.28914

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.