human AMBRA1 Adenovirus

Name 
Ad-h-AMBRA1
Cat No 
ADV-200836
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human AMBRA1.

ADV-200836
Ad-h-AMBRA1

Ready-to-use Adenovirus expressing Human AMBRA1 (autophagy and beclin 1 regulator 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
activating molecule in beclin-1-regulated autophagy; activating molecule in BECN1-regulated autophagy protein 1; autophagy/beclin-1 regulator 1; DCAF3; DDB1 and CUL4 associated factor 3; WD repeat domain 94; WDR94
Description (eCommerce)
AMBRA1 (activating molecule in Beclin-1-regulated autophagy protein 1) is a protein that bears a WD40 domain and regulates Beclin-1-dependent autophagy. In mouse embryos AMBRA1 has been shown to be critical for neural tube development.
Gene ID
55626
Gene Name (eCommerce)
autophagy and beclin 1 regulator 1
Gene Name (Vector)
autophagy and beclin 1 regulator 1
Gene Symbol
AMBRA1
HGNC ID
HGNC:25990
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3627
ORF Size (bp)
3627 bp
Protein Name (eCommerce)
Activating molecule in BECN1-regulated autophagy protein 1
RefSeq ID
NM_017749
RefSeq Synonyms
NM_017749, NM_001300731, NM_001267783, NM_001267782, BC045609,
Research Areas
Apoptosis,Autophagy,Neurobiology,Neurodevelopment,Neurogenesis
Research Areas (Faceted)
cell_biology,developmental_biology,neurobiology
Species
human
Target Sentence
AMBRA1 (activating molecule in Beclin-1-regulated autophagy protein 1) is a protein that bears a WD40 domain and regulates Beclin-1-dependent autophagy. In mouse embryos AMBRA1 has been shown to be critical for neural tube development.
UniGene ID
Hs.654644
UniProt ID (eCommerce)
Q9C0C7

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.