human AKTIP Adenovirus
This is an Adenovirus expressing Human ADAM8.
ADV-200710
Ad-h-AKTIP
Ready-to-use Adenovirus expressing Human AKTIP (AKT interacting protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FT1; FTS
Description (Vector)
The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein.
Gene ID
64400
Gene Name (Vector)
AKT interacting protein
Gene Symbol
AKTIP
HGNC ID
HGNC:16710
ORF Size (aa)
882
RefSeq ID
NM_022476
RefSeq Synonyms
NM_022476, NM_001308325, NM_001012398, BC095401, BC001134,
Species
human
UniGene ID
Hs.380897
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.