human AHI1 Adenovirus

Name 
Ad-h-AHI1
Cat No 
ADV-200608
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human AHI1.

ADV-200608
Ad-h-AHI1

Ready-to-use Adenovirus expressing Human AHI1 (Abelson helper integration site 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
abelson helper integration site 1 protein homolog; AHI-1; contatins SH3 and WD40 domains; dJ71N10.1; JBTS3; jouberin; ORF1
Description (eCommerce)
Abelson helper integration site 1 (AHI1) is also known as jouberin. AHI1 is apparently required for both cerebellar and cortical development in humans. Mutations in AH1 cause specific forms of Joubert syndrome-related disorders. Joubert syndrome (JS) is a recessively inherited developmental brain disorder with several identified causative chromosomal loci [taken from NCBI Entrez Gene (Gene ID: 55054)].
Description (Vector)
AHI1 is apparently required for both cerebellar and cortical development in humans. AHI1 mutations cause specific forms of Joubert syndrome-related disorders. Joubert syndrome (JS) is a recessively inherited developmental brain disorder with several identified causative chromosomal loci. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
54806
Gene Name (eCommerce)
Abelson helper integration site 1
Gene Name (Vector)
Abelson helper integration site 1
Gene Symbol
AHI1
HGNC ID
HGNC:21575
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1830
ORF Size (bp)
1830 bp
Protein Name (eCommerce)
Jouberin
RefSeq ID
NM_017651
RefSeq Synonyms
NM_017651, NM_001134832, NM_001134831, NM_001134830, BC094800,
Research Areas
Apoptosis,Brain Development,Cardiology,Cardiovascular,Cytoskeleton,Neurobiology,Neurodevelopment,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology,neurobiology,developmental_biology,cardiovascular,cell_biology,neurobiology,developmental_biology
Species
human
Target Sentence
Abelson helper integration site 1 (AHI1) is also known as jouberin. AHI1 is apparently required for both cerebellar and cortical development in humans. Mutations in AH1 cause specific forms of Joubert syndrome-related disorders. Joubert syndrome (JS) is a recessively inherited developmental brain disorder with several identified causative chromosomal loci [taken from NCBI Entrez Gene (Gene ID: 55054)].
UniGene ID
Hs.386684
UniProt ID (eCommerce)
Q8N157

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.