human AFF1 Adenovirus

Name
Ad-h-AFF1

Cat No
ADV-200530

Availability
4-5 weeks

This is an Adenovirus expressing Human ACTBL2.

ADV-200530

Ad-h-AFF1

Ready-to-use Adenovirus expressing Human AFF1 (AF4/FMR2 family member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

AF4; AF4/FMR2 family member 1; ALL1-fused gene from chromosome 4 protein; MLLT2; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 2; PBM1; pre-B-cell monocytic leukemia partner 1; Protein AF-4; Protein FEL; proto-oncogene AF4

Description (eCommerce)

AF4 is a member of the AF4/LAF4/FMR2 (ALF) family of transcription cofactors. It has been identified as part of a translocation [t(4:11)(q21;q23)] found in patients with acute leukemia involving MLL/HRX. AF4 functions as a cofactor of transcriptional elongation and chromatin remodeling.

Gene ID

4299

Gene Name (eCommerce)

AF4/FMR2 family member 1

Gene Name (Vector)

AF4/FMR2 family member 1

Gene Symbol

AFF1

HGNC ID

HGNC:7135

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

3636

ORF Size (bp)

3636 bp

Protein Name (eCommerce)

AF4/FMR2 family member 1

RefSeq ID

NM_005935

RefSeq Synonyms

NM_005935, NM_001313960, NM_001313959, NM_001166693, BC114930,

Research Areas

Cancer,Chromatin Remodeling,Transcription Factor/Regulator,Transcriptional Misregulation in Cancer,Tumor Suppressors/Oncoproteins

Research Areas (Faceted)

cancer,cell_biology,genetics,transcription_translation,cancer,cancer,transcription_translation

Species

human

Target Sentence

UniGene ID

Hs.480190

UniProt ID (eCommerce)

P51825

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.