human ACTA1 Adenovirus

Name
Ad-h-ACTA1

Cat No
ADV-200267

Availability
4-5 weeks

This is an Adenovirus expressing Human ACTA1.

ADV-200267

Ad-h-ACTA1

Ready-to-use Adenovirus expressing Human ACTA1 (actin, alpha 1, skeletal muscle). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

ACTA; ASMA; CFTD; CFTD1; CFTDM; MPFD; NEM1; NEM2; NEM3; SHPM

Description (Vector)

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

Gene ID

Gene Name (Vector)

actin, alpha 1, skeletal muscle

Gene Symbol

ACTA1

HGNC ID

HGNC:129

ORF Size (aa)

1134

RefSeq ID

NM_001100

RefSeq Synonyms

NM_001100, BC012597,

Species

human

UniGene ID

Hs.1288

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.