human ABCG8 Adenovirus
This is an Adenovirus expressing Human ABCG8.
ADV-200103
Ad-h-ABCG8
Ready-to-use Adenovirus expressing Human ABCG8 (ATP binding cassette subfamily G member 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GBD4; STSL
Description (Vector)
ABCG8 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. ABCG8 functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia.
Gene ID
64241
Gene Name (Vector)
ATP binding cassette subfamily G member 8
Gene Symbol
ABCG8
HGNC ID
HGNC:13887
ORF Size (aa)
2022
ORF Size (bp)
2022 bp
RefSeq ID
NM_022437
RefSeq Synonyms
NM_022437, BC143564, BC113657,
Species
human
UniGene ID
Hs.413931
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.