human ABCB1 Adenovirus
Category: Adenovirus > Over-Expression
Cat. No: ADV-200056
Availability:
3-5 weeks
Name:
Ad-h-ABCB1
This is an Adenovirus expressing Human ABCB1.
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Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- CMV
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- ABCB1
- Gene Name
- ATP binding cassette subfamily B member 1
- Gene ID
- 5243
- Gene Synonyms
- ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1
- ORF Size
- 3843 bp
- RefSeq#
- BC130424
- Gene Description
- The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
- UniGene ID
- Hs.489033
- HGNC ID
- HGNC:40
Related Products
Product | Cat No. |
---|---|
Ad-h-MDR1-shRNA | 1848 |
AAV-h-ABCB1-shRNA | shAAV-200056 |
Ad-h-ABCB1-shRNA | shADV-200056 |
Control Products
Product | Cat No. |
---|---|
Ad-CMV-Luc | 1000 |
Ad-GFP | 1060 |
Ad-CMV-b-Gal | 1080 |
Ad-Null | 1240 |
Ad-CMV-Null | 1300 |
Ad-RFP | 1660 |
Ad-CFP | 1766 |
Ad-mCherry | 1767 |
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