rat CYP1A2 Over-expression AAV

Name 
AAV-r-CYP1A2
Cat No 
AAV-295068
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Rat Cyp1a2.

AAV-295068
AAV-r-CYP1A2

Ready-to-use AAV expressing Rat Cyp1a2 (cytochrome P450, family 1, subfamily a, polypeptide 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CYPD45; P-450d; RATCYPD45
Description (Vector)
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.
Gene ID
24297
Gene Name (Vector)
cytochrome P450, family 1, subfamily a, polypeptide 2
Gene Symbol
Cyp1a2
ORF Size (aa)
1542
ORF Size (bp)
1542 bp
RefSeq ID
NM_012541
RefSeq Synonyms
NM_012541, BC127476,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.