rat TNF Over-expression AAV

Name 
AAV-r-TNF
Cat No 
AAV-294787
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Rat Tnf.

AAV-294787
AAV-r-TNF

Ready-to-use AAV expressing Rat Tnf (tumor necrosis factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
RATTNF; TNF-alpha; Tnfa
Description (Vector)
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation|Function: The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
Gene ID
24835
Gene Name (Vector)
tumor necrosis factor
Gene Symbol
Tnf
ORF Size (aa)
708
ORF Size (bp)
708 bp
RefSeq ID
NM_012675
RefSeq Synonyms
NM_012675, BC107671,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.