rat GRB2 Over-expression AAV

Name
AAV-r-GRB2

Cat No
AAV-293317

Availability
4-5 weeks

This is an AAV expressing Rat Grb2.

AAV-293317

AAV-r-GRB2

Ready-to-use AAV expressing Rat Grb2 (growth factor receptor bound protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Ash-psi

Description (Vector)

Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway|Function: Isoform 2 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform 2 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.

Gene ID

81504

Gene Name (Vector)

growth factor receptor bound protein 2

Gene Symbol

Grb2

ORF Size (aa)

654

ORF Size (bp)

654 bp

RefSeq ID

NM_030846

RefSeq Synonyms

NM_030846, BC091144,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.