rat FAIM3 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-292771
Availability:
3-5 weeks
Name:
AAV-r-FAIM3
This is an AAV expressing Rat Fcmr.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Rat
- Gene Symbol
- Fcmr
- Gene Name
- Fc fragment of IgM receptor
- Gene ID
- 548326
- Gene Synonyms
- Faim3; Toso
- ORF Size
- 1281 bp
- RefSeq#
- BC088197
- Gene Description
- FAIM3 may play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
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