rat PHLDA3 Over-expression AAV
This is an AAV expressing Rat Phlda3.
AAV-292432
AAV-r-PHLDA3
Ready-to-use AAV expressing Rat Phlda3 (pleckstrin homology-like domain, family A, member 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its directs transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May acts as a tumor suppressor.
Gene ID
363989
Gene Name (Vector)
pleckstrin homology-like domain, family A, member 3
Gene Symbol
Phlda3
ORF Size (aa)
378
RefSeq ID
NM_001012206
RefSeq Synonyms
NM_001012206, BC087038,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.