rat TNFRSF1A Over-expression AAV

Name 
AAV-r-TNFRSF1A
Cat No 
AAV-292225
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Rat Tnfrsf1a.

AAV-292225
AAV-r-TNFRSF1A

Ready-to-use AAV expressing Rat Tnfrsf1a (TNF receptor superfamily member 1A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
TNFR-1; Tnfr1
Description (Vector)
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
Gene ID
25625
Gene Name (Vector)
TNF receptor superfamily member 1A
Gene Symbol
Tnfrsf1a
ORF Size (aa)
1386
ORF Size (bp)
1386 bp
RefSeq ID
NM_013091
RefSeq Synonyms
NM_013091, BC086413,
Species
rat

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.