rat GGT1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-291948
Availability:
3-5 weeks
Name:
AAV-r-GGT1
This is an AAV expressing Rat Ggt1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Rat
- Gene Symbol
- Ggt1
- Gene Name
- gamma-glutamyltransferase 1
- Gene ID
- 116568
- Gene Synonyms
- GGLUT; Ggt; Ggtp
- ORF Size
- 1707 bp
- RefSeq#
- BC078768
- Gene Description
- Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors. Alternatively, glutathione can be hydrolyzed to give Cys-Gly and gamma glutamate. Isoform 3 seems to be inactive.
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