rat IRGM Over-expression AAV

Name
AAV-r-IRGM

Cat No
AAV-291251

Availability
4-5 weeks

This is an AAV expressing Rat Irgm.

AAV-291251

AAV-r-IRGM

Ready-to-use AAV expressing Rat Irgm (immunity-related GTPase M). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Ifggd3; Ifi1

Description (Vector)

Putative GTPase which is required for clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. May also play a role in macrophages adhesion and motility (By similarity).

Gene ID

303090

Gene Name (Vector)

immunity-related GTPase M

Gene Symbol

Irgm

ORF Size (aa)

1236

ORF Size (bp)

1236 bp

RefSeq ID

NM_001012007

RefSeq Synonyms

NM_001012007, BC079106,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.