rat MAP3K11 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-290751
Availability:
3-5 weeks
Name:
AAV-r-MAP3K11
This is an AAV expressing Rat Map3k11.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Rat
- Gene Symbol
- Map3k11
- Gene Name
- mitogen-activated protein kinase kinase kinase 11
- Gene ID
- 309168
- Gene Synonyms
- Mlk-3; Mlk3; RHOE
- ORF Size
- 2553 bp
- RefSeq#
- BC081952
- Gene Description
- Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.
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