rat PPP1R15A Over-expression AAV

Name
AAV-r-PPP1R15A

Cat No
AAV-290706

Availability
4-5 weeks

This is an AAV expressing Rat Ppp1r15a.

AAV-290706

AAV-r-PPP1R15A

Ready-to-use AAV expressing Rat Ppp1r15a (protein phosphatase 1, regulatory subunit 15A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Gadd34; Myd116; Peg-3; RGD1624209

Description (Vector)

Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.

Gene ID

171071

Gene Name (Vector)

protein phosphatase 1, regulatory subunit 15A

Gene Symbol

Ppp1r15a

ORF Size (aa)

1737

ORF Size (bp)

1737 bp

RefSeq ID

NM_133546

RefSeq Synonyms

NM_133546, BC072513,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.