rat PTBP1 Over-expression AAV

Name
AAV-r-PTBP1

Cat No
AAV-290482

Availability
4-5 weeks

This is an AAV expressing Rat Ptbp1.

AAV-290482

AAV-r-PTBP1

Ready-to-use AAV expressing Rat Ptbp1 (polypyrimidine tract binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Ptb; PTB1; Pybp; Pybp1; Pybp2

Description (Vector)

Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10.

Gene ID

29497

Gene Name (Vector)

polypyrimidine tract binding protein 1

Gene Symbol

Ptbp1

ORF Size (aa)

1671

ORF Size (bp)

1671 bp

RefSeq ID

NM_001271057

RefSeq Synonyms

NM_022516, NM_001271057, BC061858,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.