rat NR2C1 Over-expression AAV

Name 
AAV-r-NR2C1
Cat No 
AAV-290463
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Rat Nr2c1.

AAV-290463
AAV-r-NR2C1

Ready-to-use AAV expressing Rat Nr2c1 (nuclear receptor subfamily 2, group C, member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Psg4; Tr2; TR2-11
Description (Vector)
Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.
Gene ID
252924
Gene Name (Vector)
nuclear receptor subfamily 2, group C, member 1
Gene Symbol
Nr2c1
ORF Size (aa)
1773
ORF Size (bp)
1773 bp
RefSeq ID
NM_145780
RefSeq Synonyms
NM_145780, BC061822,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.