mouse RNF111 Over-expression AAV
This is an AAV expressing Mouse Rnf111.
AAV-281054
AAV-m-RNF111
Ready-to-use AAV expressing Mouse Rnf111 (ring finger 111). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ARK; Arkadia
Description (Vector)
Acts in the NODAL pathway of mesoderm patterning during embryonic development. Acts downstream AXIN1 as an E3 ubiquitin-protein ligase which promotes the ubiquitination of inhibitory SMADs such as SMAD7, induces their proteasomal degradation and thereby enhances the transcriptional activity of TGF-beta and BMP. Activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation.
Gene ID
93836
Gene Name (Vector)
ring finger 111
Gene Symbol
Rnf111
ORF Size (aa)
2946
ORF Size (bp)
2946 bp
RefSeq ID
NM_033604
RefSeq Synonyms
NM_033604, BC069835,
Species
mouse
UniGene ID
Mm.29783
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.