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mouse DNAJB6 Over-expression AAV

Name 
AAV-m-DNAJB6
Cat No 
AAV-279172
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Dnajb6.

AAV-279172
AAV-m-DNAJB6

Ready-to-use AAV expressing Mouse Dnajb6 (DnaJ heat shock protein family (Hsp40) member B6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
mDj4; Mrj
Description (Vector)
Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Isoform B but not isoform A inhibits huntingtin aggregation. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity.
Gene ID
23950
Gene Name (Vector)
DnaJ heat shock protein family (Hsp40) member B6
Gene Symbol
Dnajb6
ORF Size (aa)
729
RefSeq ID
NM_011847
RefSeq Synonyms
NM_011847, NM_001127367, NM_001037941, NM_001037940, BC083349, BC003702,
Species
mouse
UniGene ID
Mm.290110

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.